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Focal Nodular Hyperplasia

Focal nodular hyperplasia, the second most common benign hepatic tumor, must be distinguished from other hypervascular hepatic lesions, such as hepatocellular carcinoma, adenoma, and metastases. MR combines information about the morphology, the enhancement features, and the presence of functioning hepatocytes within these tumors to differentiate FNH from other hepatic tumors.

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  1. Agnello F, Ronot M, Valla DC, Sinkus R, Van Beers BE, Vilgrain V. High-b-value diffusion-weighted MR imaging of benign hepatocellular lesions: quantitative and qualitative analysis. Radiology 2012; 262:511-519. PubMed link
  2. Grazioli L, Morana G, Kirchin MA, Schneider G. Accurate differentiation of focal nodular hyperplasia from hepatic adenoma at gadobenate dimeglumine-enhanced MR imaging: prospective study. Radiology 2005; 236:166-177. PubMed link
  3. Hussain SM, Terkivatan T, Zondervan PE, et al. Focal nodular hyperplasia: findings at state-of-the-art MR imaging, US, CT, and pathologic analysis. Radiographics 2004; 24:3-17; discussion 18-19. PubMed link
  4. Karam AR, Shankar S, Surapaneni P, Kim YH, Hussain S. Focal nodular hyperplasia: central scar enhancement pattern using Gadoxetate Disodium. J Magn Reson Imaging 2010; 32:341-344. PubMed link
  5. Purysko AS, Remer EM, Coppa CP, Obuchowski NA, Schneider E, Veniero JC. Characteristics and distinguishing features of hepatocellular adenoma and focal nodular hyperplasia on gadoxetate disodium-enhanced MRI. AJR Am J Roentgenol 2012; 198:115-123. PubMed link
  6. Shamsi K, De Schepper A, Degryse H, Deckers F. Focal nodular hyperplasia of the liver: radiologic findings. Abdom Imaging 1993; 18:32-38. PubMed link