Research
Body MRI research at Stanford is fostered by a tight link between research scientists in the Department of Radiology, the University, and throughout the Bay Area. Clinical scanners have platforms identical to dedicated research scanners, enabling rapid clinical translation. These efforts are supported by multiple NIH grants.
MR-Guided Focused Ultrasound (MRgFUS) for Prostate Cancer & MR-Guided Cryoablation with Nirogacestat for Desmoid Tumors
Research in MR-guided interventional radiology has led to groundbreaking advancements in the treatment of various medical conditions, including prostate cancer and desmoid tumors
High-Resolution Motion-Robust Abdominal DWI
MRI is attractive in cancer imaging due to superior soft tissue contrast and multiparametric capabilities.
Diffusion weighted Imaging
Moving beyond single-shot echo planar imaging for diffusion weighted imaging in the prostate.
Pelvic Floor Dysfunction
Pelvic floor disorders are very common and disparate group of conditions with significant impacts on patients daily lives.
Endometriosis & Ovarian lesion characterization
Endometriosis detection and assessing severity can be performed with MRI. Ovarian lesion characterization with MRI increases diagnosis specificity.
Motion Robust MRI
A large challenge in MRI remains blurring, artifacts, and reduced image quality that comes from patient motion.
- Bowel Endometriosis: Systematic Approach to Diagnosis with US and MRIon March 20, 2025
Endometriosis involving the bowel is a severe form of the disease, and the bowel is the most common site of extragenital endometriosis. Surface lesions of the bowel are considered peritoneal disease. Bowel endometriosis (BE) is defined as […]
- Cost-effectiveness of novel diagnostic tools for idiopathic pulmonary fibrosis in the United Stateson March 16, 2025
CONCLUSIONS: Novel tools for diagnosing IPF reduced diagnostic costs, while overall incremental cost-effectiveness ratios were high due to treatment costs. New IPF diagnosis approaches may become more favourable with lower-cost treatments for IPF.
- AI-ready rectal cancer MR imaging: a workflow for tumor detection and segmentationon March 15, 2025
CONCLUSION: This study demonstrates the feasibility of generating high-quality labeled MR datasets through collaboration between a radiologist and two data scientists, which is essential for training AI models to automate tumor detection and […]
- Diffusion-prepared imaging with amplitude navigation for correction of motion-induced signal losson March 4, 2025
CONCLUSION: Employing amplitude weights in the reconstruction of a diffusion-prepared sequence can improve SNR efficiency at the cost of a greater minimum sampling time and increased sensitivity to B(1) inhomogeneity.
- ScreenDx, an artificial intelligence-based algorithm for the incidental detection of pulmonary fibrosison February 28, 2025
CONCLUSION: Regardless of CT manufacturer or slice thickness, ScreenDx demonstrated high performance across two, multi-site datasets for identifying incidental cases of pulmonary fibrosis. This suggest that the algorithm may be generalizable across […]
- ProstAtlasDiff: Prostate cancer detection on MRI using Diffusion Probabilistic Models guided by population spatial cancer atlaseson February 19, 2025
Magnetic Resonance Imaging (MRI) is increasingly being used to detect prostate cancer, yet its interpretation can be challenging due to subtle differences between benign and cancerous tissue. Recently, Denoising Diffusion Probabilistic Models […]
- Using deep feature distances for evaluating the perceptual quality of MR image reconstructionson February 8, 2025
CONCLUSION: A suite of IQ metrics, including DFDs and HFEN, should be used alongside commonly-reported IQ metrics for a more holistic evaluation of MR image reconstruction perceptual quality. We also observe that general vision encoders are capable […]
- ProCUSNet: Prostate Cancer Detection on B-mode Transrectal Ultrasound Using Artificial Intelligence for Targeting During Prostate Biopsieson January 29, 2025
CONCLUSIONS AND CLINICAL IMPLICATIONS: ProCUSNet can localize clinically significant cancer on screen capture B-mode ultrasound, a task that is particularly challenging for clinicians reading these examinations. As a supplement to systematic […]
- Predictive Value of Magnetic Resonance Complete Response After Neoadjuvant Therapy for Rectal Canceron January 28, 2025
CONCLUSIONS: The value of mrCR in predicting pathologic response following neoadjuvant therapy in locally advanced rectal cancer is low, and mrCR should be interpreted with caution when counseling patients about nonoperative management. Early, […]
- MRI features that predict progression of residual disease after ablation of extra-abdominal desmoid fibromatosison January 21, 2025
OBJECTIVE: To identify MRI features of desmoid tumors (DTs) that predict the growth of residual disease following ablation.
- Motion-Compensated Multishot Pancreatic Diffusion-Weighted Imaging With Deep Learning-Based Denoisingon January 17, 2025
CONCLUSIONS: CODE-generated motion compensating gradients improves multishot pancreatic DWI as interpreted by expert readers and eliminated ADC variation throughout the pancreas. DL-based denoising mitigated signal losses from motion compensation […]
- T2 Clusters Are More Sensitive Than Mean T2 Change to Detect Early and Longitudinal Changes in Anterior Cruciate Ligament Reconstructed and Healthy Kneeson December 31, 2024
CONCLUSION: T(2)C metrics are more sensitive than ΔT(2)Mean for longitudinal monitoring of femoral cartilage post ACLR. Our findings suggest potential merging of T(2) clusters overtime, forming larger areas of cartilage degradation in ACLR knees.
- Spatial transcriptomic analysis drives PET imaging of tight junction protein expression in pancreatic cancer theranosticson December 31, 2024
Molecular imaging using positron emission tomography (PET) provides sensitive detection and mapping of molecular targets. While cancer-associated fibroblasts and integrins have been proposed as targets for imaging of pancreatic ductal adenocarcinoma […]
- The Challenge of External Generalisability: Insights from the Bicentric Validation of a [68Ga]Ga-PSMA-11 PET Based Radiomics Signature for Primary Prostate Cancer Characterisation Using Histopathology as Referenceon December 17, 2024
Background: PSMA PET radiomics is a promising tool for primary prostate cancer (PCa) characterisation. However, small single-centre studies and lack of external validation hinder definitive conclusions on the potential of PSMA PET radiomics in the […]
- Imaging Findings and Management Strategies for Liver Masses in Children with Predisposition Disorders: A Review by the Pediatric LI-RADS Groupon December 12, 2024
Liver masses in children with underlying systemic disease or a predisposing syndrome can be benign or malignant, ranging from focal fat to hepatocellular carcinoma (HCC). Knowledge of the underlying condition, the pathophysiologic effect on the […]
- "Quality over quantity:" smaller, targeted lesions optimize quality of life outcomes after MR-guided focused ultrasound thalamotomy for essential tremoron November 29, 2024
INTRODUCTION: MRI-guided focused ultrasound (MRgFUS) thalamotomy of the nucleus ventralis intermedius (VIM) has emerged as a powerful and safe treatment modality for refractory essential tremor. While the efficacy of this technique has been […]
- Invited Commentary: Augmented Pelvic US: Path Forward to Reduce Delays in Diagnosis of Endometriosison November 21, 2024
No abstract
- Postmenopausal Endometriosis: Clinical Insights and Imaging Considerationson November 14, 2024
Endometriosis is a chronic systemic condition characterized by the presence of ectopic endometrial-like tissue outside of the uterus. It occurs most often in reproductive-aged patients and less frequently in postmenopausal women. In postmenopausal […]
- Aggressiveness classification of clear cell renal cell carcinoma using registration-independent radiology-pathology correlation learningon October 24, 2024
CONCLUSION: CorrFABR provides a novel method for CT-based aggressiveness classification of ccRCC by enabling the identification of pathology-informed CT biomarkers, and integrating them with clinical variables. CorrFABR enables learning of these […]
- Real World Outcome of High-Risk Multiple Myeloma: An Indian Tertiary Care Centre Experienceon October 19, 2024
INTRODUCTION: High risk myeloma is heterogeneous with significant variation in risk stratifications. Real world outcomes differ from controlled clinical trials and affected by socioeconomical determinants.
- Reply to Letter to the Editor: "What predicts durable symptom relief of uterine fibroids treated with MRI-guided focused ultrasound? A multi-center trial in 8 academic centers"on October 18, 2024
No abstract
- Nested Semi-Transparent Isosurface Simulated Volume-Rendering (NESTIS-VR) - An efficient on-device rendering approach for Augmented Reality headsets increasing surgeon confidence of kidney donor arterial anatomyon October 15, 2024
CONCLUSION: NESTIS-VR provides a new approach to rendering medical datasets in computationally limited OST-HMD headsets and significantly increases surgeons' confidence of kidney donor arterial anatomy. The principal confidence benefit arises from […]
- The Ovarian-Adnexal Reporting and Data System (O-RADS) US Score Effect on Surgical Resection Rateon October 8, 2024
Background The Ovarian-Adnexal Imaging Reporting and Data System (O-RADS) US risk score can be used to accurately stratify ovarian lesions based on morphologic characteristics. However, there are no large multicenter studies assessing the potential […]
- Trends in pre-biopsy MRI usage for prostate cancer detection, 2007-2022on September 21, 2024
CONCLUSIONS: The study reveals a paradigm shift in prostate cancer diagnostics towards MRI-guided approaches, influenced by evolving guidelines and clinical evidence. Disparities in access, particularly in rural areas and specific regions, highlight […]
- Radiology State-of-the-art Review: Endometriosis Imaging Interpretation and Reportingon September 17, 2024
Endometriosis is a common condition impacting approximately 190 million individuals and up to 50% of women with infertility globally. The disease is characterized by endometrial-like tissue located outside of the uterine corpus, which causes […]
- Editorial for "Multiparametric MRI Scoring System of the Pancreas for the Diagnosis of Chronic Pancreatitis"on September 16, 2024
No abstract
- Parametric response mapping of co-registered intravoxel incoherent motion magnetic resonance imaging and positron emission tomography in locally advanced cervical cancer undergoing concurrent chemoradiation therapyon September 12, 2024
CONCLUSION: IVIM and PET was performed on cervical cancer patients undergoing CCRT and we observed that both IVIM-f and IVIM-D increased during treatment. Additionally, PRM was applied, and sub-volumes were identified that were related to ΔGTV.
- A diffusion-prepared reduced FOV sequence for prostate MRI near metallic implantson September 2, 2024
CONCLUSION: Acquisition of distortionless diffusion weighted images of the prostate is feasible in patients with total hip replacements on conventional, whole-body 3T MRI, using a b-value of 800 s / mm 2 $$ \mathrm{s}/{\mathrm{mm}}^2 $$ and […]
- Intraprocedural Diffusion-weighted Imaging for Predicting Ablation Zone during MRI-guided Focused Ultrasound of Prostate Canceron August 30, 2024
Purpose To compare diffusion-weighted imaging (DWI) with thermal dosimetry as a noncontrast method to predict ablation margins in individuals with prostate cancer treated with MRI-guided focused ultrasound (MRgFUS) ablation. Materials and Methods […]
- The Roles of Ovarian-Adnexal Reporting and Data System US and Ovarian-Adnexal Reporting and Data System MRI in the Evaluation of Adnexal Lesionson August 20, 2024
The Ovarian-Adnexal Reporting and Data System (O-RADS) is an evidence-based clinical support system for ovarian and adnexal lesion assessment in women of average risk. The system has both US and MRI components with separate but complementary […]